Home Chemistry General Organic Chemistry Organic Reaction Mechanisms - I The relative reactivity of acyl compounds to…
Chemistry General Organic Chemistry Organic Reaction Mechanisms - I Single Correct MCQ
Published on: August 14, 2026

The relative reactivity of acyl compounds towards nucleophilic substitution are in the order of :

A
Acid anhydride > Amide > Ester > Acyl chloride
B
Acyl chloride > Ester > Acid anhydride > Amide
C
Acyl chloride > Acid anhydride > Ester > Amide
D
Ester > Acyl chloride > Amide > Acid anhydride

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The correct answer is:
C

The reactivity towards nuecleophilic substitution reaction is

Acyl chloride > Acid anhydride > Ester > Amide

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